The meeting will be divided in several sections that will explore basic and complex splicing mechanisms and their regulation, the connections of this process with epigenetic, genome modifications, and non-coding RNAs, and finally the role played by this process in disease. The conference aims to gather former EURASNET project members as well as non-EURASNET participants interested in the regulation and role of alternative splicing.
EURASNET was the Alternative Splicing Network of Excellence funded by the Framework 6 Programme (FP6) of the European Union (2006 - 2010). The network aimed to explain the mechanisms of alternative splicing, established a communication platform among researchers, supported Young Investigators to establish new research groups, and raised awareness of the importance of alternative splicing among clinicians, policy makers and the general public.
EURASNET was an EU-funded Network of Excellence to investigate and understand the principles of alternative splicing and how it affects human health.
The Alternative Splicing Network of Excellence brought together 30 leading research groups and ten Young Investigators, from eleven European countries as well as Israel and Argentina. The co-ordinator of this Network was Professor Reinhard Lührmann, Göttingen. The network had funding for a period of five years (2006-2011) from Framework 6 Programme (FP6) of the European Union, for research in alternative splicing.
The EURASNET consortium employed a wide range of complementary approaches such as computational, biochemical, proteomic, genomic, cell and organismal biology to study post-transcriptional gene regulation and its role in disease.
The network had four main objectives:
Develop an integrated approach for the study of alternative splicing to elucidate the regulatory mechanisms and significance of alternative splicing, at the molecular, cellular and organismal level with a strong focus on alternative splicing events that are related to genetic disease.
Establish an innovative and multi-disciplinary programme of joint research activities for the exchange of information, methods and material among the network partners.
Spread excellence within Europe by establishing a career platform for ten ‘Young Investigators’.
Raise awareness of the importance of alternative splicing among medical practitioners, policy makers and the general public.
EURASNET was supported by a scientific advisory board made up of eminent international scientists: J. Dahlberg (University of Madison), W. Filipowicz (Biozentrum Basel), M. Garcia-Blanco (Duke University), A. Krainer (Cold Spring Harbor L), M. Rosbash (Brandeis University), R. Singer (Albert Einstein College) and J. Steitz (Yale University).
To see conference program, click here.
Informację wprowadził/a: Joanna Zadarko